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Improved Programmed Intermittent Epidural Bolus Volume Regimen in the Setting of Labor Analgesia

Improved Programmed Intermittent Epidural Bolus Volume Regimen in the Setting of Labor Analgesia

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100043816
Enrollment
Unknown
Registered
2021-03-04
Start date
2021-03-05
Completion date
Unknown
Last updated
2021-07-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor pain

Interventions

CEI 8:8 ml/h continuous epidural infusion
PIEB 6:6 ml/h programmed intermittent epidural bolus
PIEB 8:8 ml/h programmed intermittent epidural bolus
PIEB 10:10 ml/h programmed intermittent epidural bolus

Sponsors

The Second Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Subjects aged 18-45 years old; 2. Asai-ii subjects; 3. Subjects who signed informed consent voluntarily; 4. Singleton subjects; 5. 18 <= BMI <= 26kg / m2 subjects; 6. Subjects with dilatation of 2-4cm; 7. Subjects with gestational age of 37-42 weeks.

Exclusion criteria

Exclusion criteria: 1. Subjects who refused epidural labor analgesia; 2. Subjects with contraindications to intraspinal anesthesia; 3. Pregnant women allergic to local anesthetics or opioids. 4. The basal body temperature of the parturient who had fever before labor analgesia was more than 37.5 degrees C; 5. Subjects with severe systemic diseases; 6. Subjects who delivered within 2 hours after labor analgesia; 7. Subjects who used opioids within 3 months.

Design outcomes

Primary

MeasureTime frame
VAS pain score;

Secondary

MeasureTime frame
Side effect;Motor block;Duration;Hourly ropivacaine consumption ;Number of rescue boluses ;

Countries

China

Contacts

Public ContactMingpin Hu

The Second Affiliated Hospital of Wenzhou Medical University

hmp2008mz@163.com+86 13705880737

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026