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The efficacy and mechanism of fecal microbiota transplantation in the treatment of patients with ulcerative colitis

The efficacy and mechanism of fecal microbiota transplantation in the treatment of patients with ulcerative colitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100043797
Enrollment
Unknown
Registered
2021-02-28
Start date
2018-01-01
Completion date
Unknown
Last updated
2021-06-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative colitis

Interventions

Case series:Single or multiple FMT were performed via the working channel of the colonoscope or transendoscopic enteral tubing in 2 months. All patients were given concomitant oral mesalamine (4g/d)

Sponsors

Department of Gastroenterology, Jinan Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
21 Years to 81 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged >=18 years; 2. Meet the clinical diagnostic criteria of moderate to severe ulcerative colitis defined as a Mayo score >=6 and an endoscopic Mayo score >=2; 3. The patient had good compliance and were willing to complete the study and follow-up.

Exclusion criteria

Exclusion criteria: 1. Patients who had history of tumors, bowel surgeries, severe heart disease, kidney disease, neurological diseases, nutritional and metabolic diseases; 2. Patients who had infections of Clostridium difficile, Escherichia coli, Salmonella, Shigella; parasites; hepatitis viruses, HIV, CMV and EBV; 3. Within one month before FMT, the patient had used antibiotics.

Design outcomes

Primary

MeasureTime frame
Effective rate;

Secondary

MeasureTime frame
Adverse events;

Countries

China

Contacts

Public ContactZhao Yin

Jinan Central Hospital

yzball86@163.com+86 13969078393

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026