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Dynamic PET-CT automatic segmentation active contour algorithm (MASAC) for monitoring the efficacy of neoadjuvant chemotherapy in nasopharyngeal carcinoma and its application in automatic target mapping:a prospective exploratory study

Dynamic PET-CT automatic segmentation active contour algorithm (MASAC) for monitoring the efficacy of neoadjuvant chemotherapy in nasopharyngeal carcinoma and its application in automatic target mapping: a prospective exploratory study

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100043787
Enrollment
Unknown
Registered
2021-02-28
Start date
2021-02-25
Completion date
Unknown
Last updated
2021-06-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nasopharyngeal carcinoma

Interventions

case series:none

Sponsors

The Fifth Affiliated Hospital of Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: A. Stage II-IVB nasopharyngeal carcinoma was diagnosed in our hospital; B. Age between 18 and 70 years; C. Nasopharyngeal carcinoma is histologically or cytologically confirmed; D. Behavior status score ECOG: 0-1 points; E. Normal bone marrow, liver and kidney function.

Exclusion criteria

Exclusion criteria: A. New program has previously received anti-tumor treatment for nasopharyngeal carcinoma (chemotherapy, radiation, targeted therapy, or immunotherapy); B. has suffered from other malignancies for nearly three years; C. Any unstable systemic disease, including active infection, uncontrolled hypertension, unstable anginal, myocardial infarction (), (6 months), cardiac function failure (cardiac function), severe cardiac arrhythmia, severe liver and kidney disease; D. the opposite of the medicine; E. hepatitis b, hepatitis c or HIV positive; F. pregnancy or lactating woman; G. The g. researchers determined that the patient was not involved.

Design outcomes

Primary

MeasureTime frame
complete response;partial response;partial response;progressive disease;standard uptake value;influx constant,Ki;

Countries

China

Contacts

Public ContactZhigang Liu

The Fifth Affiliated Hospital of Sun Yat-Sen University

zhigangliu1983@hotmail.com+86 18627585860

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026