Disorders of Consciousness
Conditions
Interventions
Median nerve stimulation group:Median nerve electrical stimulation (MNS)
Transcranial direct current stimulation group:Transcranial direct current stimulation (tDCS)
Median nerve electrical stimulation + transcranial magnetic stimulation group:MNS+TMS
Median nerve electrical stimulation + transcranial direct current stimulation group:MNS+tDCS
Control group:Conventional rehabilitation
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. Craniocerebral injury is the main pathogenic factor and confirmed by CT and (or) MRI of the brain, accompanied by disturbance of consciousness, and craniocerebral injury is the only pathogenic factor; 3. Course of DOC>= 28 days; 4. DOC is assessed by Glasgow coma scale (GCS) ( 2 points or vision> 1 point or sports > 2 points or speech response > 2 points or communication > 0 points or arousal > 2 points) by CRS-R; 5. Stable vital signs; 6. The patients' family members are informed and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with critical illness and unstable vital signs; 2. Active cerebral hemorrhage; 3. Patients with metal objects in the brain; 4. Pacemakers in the body; 5. Unconsciousness caused by other reasons; 6. Past history of epilepsy or family history of epilepsy; 7. Severe heart, liver, kidney and other vital organ failure; 8. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| GCS;CRS-R;full outline of unresponsiveness (FOUR); | — |
Secondary
| Measure | Time frame |
|---|---|
| evoked potentials;electroencephalogram;CT perfusion;adverse event; | — |
Countries
China
Contacts
Public ContactFeng Zhen
The First Affiliated Hospital of Nanchang University
Outcome results
None listed