hepatocellular carcinoma
Conditions
Interventions
Gold Standard:Pathologic diagnosis
Index test:Optimization 
and 
evaluation 
of 
individualized 
predictive 
model 
for 
early 
hepatocellular 
based 
on 
immunomics.
Sponsors
Tianjin Medical University Cancer Institute and Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. According to China's liver cancer guidelines in 2019, patients with newly diagnosed liver cancer diagnosed by imaging or pathology; 2. Patients with single tumor = 5cm or multiple 2-3 tumors and single tumor = 3cm; 3. Child Pugh grade A or B subjects; 4. Subjects without large vessel invasion or distant metastasis.
Exclusion criteria
Exclusion criteria: 1. Subjects who had been treated with TACE or sorafenib; 2. The patients with pathological type of non HCC were other types of HCC; 3. Patients with underlying immune system diseases; 4. Patients with major underlying diseases; 5. Patients who used antibiotics within one month before admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Faecal DNA concentration;Fecal DNA purity;IL-6;IL-1ß;TNF-a;IL-17A;IL-17F;IL-22;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactWei Lu
Tianjin Medical University Cancer Institute and Hospital
Outcome results
None listed