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Systematic screening of prognostic and recurrence markers of colorectal cancer and construction of survival prediction model

Systematic screening of prognostic and recurrence markers of colorectal cancer and construction of survival prediction model

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100043775
Enrollment
Unknown
Registered
2021-02-28
Start date
2021-03-01
Completion date
Unknown
Last updated
2021-06-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

IOC group:intraoperative chemotherapy (IOC)
No-IOC group:without intraoperative chemotherapy (IOC)
Stricture:No
No stricture:No
Here 2 positive / RAS mutation / MSI-H / CTC positive:No
Here 2 negative / Ras wild /MSI-L / CTC negative:No

Sponsors

The Fourth Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Patients who were pathologically diagnosed as CRC and confirmed by histological examination; (2) patients who underwent radical surgical resection; (3) patients who were diagnosed as stage IV with resectable metastases should receive intraoperative metastasis R0 resection; (4) patients at all ages.

Exclusion criteria

Exclusion criteria: (1) Patients who were diagnosed with simultaneous and heterochronous multiple primary cancers; (2) patients who were diagnosed with appendix adenocarcinoma or other types of tumors; (3) patients with incomplete data; (4) patients with metastases found after 4-8 weeks of follow-up; (5) patients who were lost to follow-up.

Design outcomes

Primary

MeasureTime frame
overall survival;Disease free survival;

Secondary

MeasureTime frame
5-year survival rate;3-year survival rate;3-year recurrence rate;5-year recurrence rate;

Countries

China

Contacts

Public ContactGuiying Wang

The Fourth Hospital of Hebei Medical University

wangguiying@hebmu.edu.cn+86 13932186739

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026