Ultrasonic measurement of pupil to observe the dose-effect relationship between different sufentanil doses and pupillary changes

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100043771

Enrollment

Unknown

Registered

2021-02-28

Start date

2021-03-01

Completion date

Unknown

Last updated

2021-06-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nociceptive monitoring of anesthesia monitoring

Interventions

Group 1:Sufentanil 0.2µg/kg

Group 2:Sufentanil 0.4µg/kg

Group 3: Sufentanil 0.6µg/kg

Group 4:Nil

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: scheduled for surgeries under general anesthesia, 18 to 65 years old, ASA I~II.

Exclusion criteria

Exclusion criteria: General anesthesia combined with spinal anesthesia or regional nerve block surgery, BMI > 30kg/cm2, long-term use of sedative, analgesic, and psychotropic drugs, those who have taken anticholinergic drugs before surgery, long-term use of sympathetic or parasympathetic drugs,those with ophthalmologic diseases or surgeries, those with unequal pupils on both sides, those with previous cranial neuropathy, and those with arm impairment.

Design outcomes

Primary

Measure	Time frame
pupillary diameter;	—

Countries

China

Contacts

Public ContactHong Xie

The The Second Affiliated Hospital of Suzhou University

hongx93044@126.com+86 13962161588

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026