Acute lung injury in sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The diagnosis of sepsis is based on the diagnostic criteria jointly recommended by the American Association of Chest Physicians and the Society of Emergency Medicine in 1992, that is, the presence of a definite infection with at least two or more of the following: 1. Body temperature > 38 degrees C or 90 /min; 3. Breathing rate > 20/min or PAC02 12.O x l0^9 / L or 0.01. The inclusion criteria for ALI followed the diagnostic criteria proposed by the European and American Joint Conference in 1994: (1) high-risk factors; (2) acute onset, respiratory frequency or respiratory distress; (3) ALI oxygenation index (PA02 / FI02) < 300mmHg, < 200mmHg to diagnose ARDS(1mmHg -- O.1133kPa)[regardless of PEEP level]: (4) Positive chest radiograph shows patchiness in the lungs; (5) Pulmonary artery wedge pressure PAWP <= 18mmHg and clinical except for cardiogenic pulmonary edema.
Exclusion criteria
Exclusion criteria: 1. Age under 18 years old; 2. Patients with previous severe cardiac insufficiency, liver disease, kidney disease, coagulation insufficiency, combined tumor and other diseases; 3. Pregnant or lactating women; 4. Brain dead patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| plasma; | — |
Countries
China
Contacts
Shenzhen Hospital of Southern Medical University