Malignant serous cavity effusion
Conditions
Interventions
Sponsors
Shenzhen Hospital of Beijing University of Traditional Chinese Medicine (Longgang)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. The following diagnostic criteria were met (1) Patients with pathologically confirmed malignancies, but not squamous cell carcinoma; (2) Ultrasound or CT examination showed a large number of pleural effusion, pericardial effusion or peritoneal effusion; (3) Malignant tumor cells were found in the effusion. 2. Those patients who had no intraluminal injection of anticancer drugs or sclerosing agents one month before enrollment; 3. The patients with KPS score >= 60 were older than 18 years old, and the expected survival time was more than 3 months; 4. Patients without major organ system dysfunction; 5. Patients with a history of chemotherapy had stopped chemotherapy for more than 4 weeks.
Exclusion criteria
Exclusion criteria: 1. Patients with previous history of allergy to biological agents; 2. No detectable lesions were found in imaging; 3. Patients with metastasis to the central nervous system; 4. Patients with major organ dysfunction, such as congestive heart failure, malignant arrhythmia, angina pectoris requiring long-term medication, valvular heart disease, myocardial infarction and intractable hypertension; 5. Pregnant or lactating women; 6. Subjects with previously refractory mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective response rate;Therapeutic effect of TCM syndromes;Quality of life; | — |
Secondary
| Measure | Time frame |
|---|---|
| security;Overall Survival;Progress Free Survival;CEA expression in serum;VEGF expression in serum;VEGF expression in effusion; | — |
Countries
China
Contacts
Public ContactFeng Gaofei
Outcome results
None listed