Cervical cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. High-risk HPV (hrHPV) positive and cervical pathology LSIL; 2. With sexual history, no current pregnancy; 3. Aged 21 to 65 years; 4. Willing to participate and obey the regular follow-up until the end of the project.
Exclusion criteria
Exclusion criteria: 1. With history of ablation or excisional procedure for cervical dysplasia; 2. With prior hysterectomy, or prior pelvic radiation; 3. With autoimmune diseases or HIV infection, or currently taking immunosuppressants; 4. Currently participating in other research/projects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| p16(INK4a) cytology;High-risk HPV genotype;Cytology;High-risk HPV viral load;Histology;Host DNA methylation;Microbiome; | — |
Countries
China
Contacts
Peking University Shenzhen Hospital