Correlation between B27 subtype and treatment response rate in patients with ankylosing spondylitis

A prospective cohort study of the correlation between different treatment options and treatment response rates for patients with different HLA-B27 subtypes of ankylosing spondylitis

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100043668

Enrollment

Unknown

Registered

2021-02-26

Start date

2021-02-26

Completion date

Unknown

Last updated

2021-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ankylosing Spondylitis

Interventions

HLA-B27 subtypes:Nil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Sign the informed consent form voluntarily; 2) Aged >= 18 years, no gender limit; 3) Meet the New York AS classification standard revised in 1984; 4) HLA-B27 is positive.

Exclusion criteria

Exclusion criteria: 1) History of malignant tumor; 2) Have a history of mental illness or a family history of mental illness; 3) Those who cannot cooperate with the investigation due to objective factors.

Design outcomes

Primary

Measure	Time frame
nocturnal back pain VAS;General back pain VAS;Patient's global assessment VAS, PGA;Bath Ankylosing Spondylitis Disease Activity Index, BASDAI;Bath Ankylosing Spondylitis Functional Index, BASFI;Ankylosing spondylitis quality of life, ASQoL;Ankylosing spondylitis disease AS activity score, ASDAS;ASAS20/40;	—

Countries

China

Contacts

Public ContactYu Qinghong

Zhujiang Hospital, Southern Medical University,

yuqinghong@smu.edu.cn+86 20-61643384

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026