Eczema
Conditions
Interventions
5-FU+TA group:2 mL normal saline (Shanghai Xudong Haipu Pharmaceutical Co., Ltd.) was mixed well with 1 mL 5-FU solution (Shanghai Xudong Haipu Pharmaceutical Co., Ltd.) (containing 25 mg 5-FU) and 1
TA group:3 mL of normal saline was mixed with 1 mL of TA solution (containing 10 mg TA).Infiltration and injection were performed to allow 1 mL of the mixture into every 4 cm2 of the skin lesion area.
Sponsors
Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital
Eligibility
Sex/Gender
All
Age
28 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 28 to 80 years old, who have given birth; 2. Meet the clinical diagnostic criteria of localized eczema, established based on the 2011 Guidelines for Eczema Diagnosis and Treatment designated by the Immunology Group, Dermatovenereology Society, Chinese Medical Association; 3. Continue Onset, duration of disease> 6 months; 4. The results of the 20 patch tests in the routine group were all negative; 5. The skin lesions had no infection or exudation; 6. The patient had good compliance, was willing to adhere to the treatment and complete the follow-up, and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Those who are allergic to triamcinolone acetonide or 5-FU; 2. Pregnant women or breastfeeding women, or those who plan to give birth or have not given birth within 12 months; 3. Hepatic and renal function test results are abnormal; 4. Hematological diseases, autoimmune diseases, chronic serious Sexual infections, diabetes, mental illness, alcoholism, malignant tumors and other serious diseases; 5. Systematic use of hormones or immunosuppressants in the past 6 weeks, and topical medication in the past 2 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| atopic dermatitis severity index (ADSI) score;Relapse rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| effctive rate; | — |
Countries
China
Contacts
Public ContactYUN WU
Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital
Outcome results
None listed