caerean section
Conditions
Interventions
PM1:Pre-injection of metaraminol 20µg*min-1 before anesthesia
PM2:Pre-injection of metaraminol 30µg*min-1 before anesthesia
PM3:Pre-injection of metaraminol 40µg*min-1 before anesthesia
PM4:Pre-injection of metaraminol 50µg*min-1 before anesthesia
Sponsors
Fujian Provincial Maternity and Children Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Inclusion criteria were elective cesarean section under spinal anesthesia, age between 18 to 40 years, healthy singleton pregnancy between 37 to 41+6 weeks gestation, American Society of Anesthesiologists (ASA) physical status I/II, height 150 to 170cm, and BMI <= 35 kg /m2.
Exclusion criteria
Exclusion criteria: Multiple pregnancy, a fetal abnormality, history of 3 or more cesarean sections, dangerous placenta previa or massive hemorrhage during perinatal period, pregnancy-induced hypertension (SBP > 140mmHg or DBP > 90mmHg), spinal anesthesia is contraindicated or refused to perform spinal anesthesia, multiple failures of spinal anesthesia puncture, combined with disease of important organs (heart, liver, kidney, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ED50;ED95; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood gas analysis of umbilical cord blood;Apgar scores at 1 and 5 min after birth;Side effects after spinal anesthesia; | — |
Countries
China
Contacts
Public ContactJing Wang
Fujian Provincial Maternity and Children Hospital
Outcome results
None listed