PCV with submacular hemorrhage
Conditions
Interventions
subretinal injection group:subretinal injection of t-PA and anti-VEGF following vitrectomy
intravitreal injection group:subretinal injection of t-PA and intravitreal of anti-VEGF following vitrectomy
Sponsors
The Eye Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Aged >= 18 years; (2) Submacular hemorrhage secondary to PCV (hemorrhage located under the retina in the macular area, involving the fovea, the area of hemorrhage does not exceed the temporal vascular arch, and the thickness does not exceed 500 µm); (3) The bleeding time is less than 1 month.
Exclusion criteria
Exclusion criteria: (1) Submacular hemorrhage caused by intraocular tumors and other reasons; (2) Those who are not expected to be followed up in the designated clinical trial center; (3) Those who have a nervous system or mental illness who cannot cooperate with the examination; (4) Those who cannot obtain informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| polypoid lesions;concentration of anti-VEGF; | — |
Secondary
| Measure | Time frame |
|---|---|
| Best corrected visual acuity;Submacular hemorrhage absorption time;Foveal thickness; | — |
Countries
China
Contacts
Public ContactYong Wei
The Eye Hospital of Wenzhou Medical University
Outcome results
None listed