rebound pain
Conditions
Interventions
Group 2:sulfentani PCIA
Group 1:esketamine combined with sulfentanil PCIA
Sponsors
Jinshan Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1)The patients were undergoing open reduction and internal fixationroutine after bone fracture; 2) 18-70 years of age; The American Society of Anesthesiologists (ASA) classification I-II; 3) Willing to cooperate and signed the informed consent
Exclusion criteria
Exclusion criteria: 1) Peripheral nerve injury or lesion; 2) Diabetic peripheral neuropathy; 3) Long-term use of painkillers or alcoholics; 4) Severe complex trauma; 5) Pregnancy; 6) Unstable angina pectoris or myocardial infarction occurred within the past six months;Severe angina pectoris is known from previous illnesses;Congestive heart failure; 7) Severe mental disorders; 8) High intraocular pressure (glaucoma) and penetrating ocular trauma; 9) Other situations in which the combination with esketamine is contraindicated.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rebound pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| sleep quality on the day of surgery;NRS pain score;time of first press, numbers of press, percentage of invalid press and total comsumption of sulfentanil on 48h after the surgery; | — |
Countries
China
Contacts
Public ContactJiahui Chen
Jinshan Hospital, Fudan University
Outcome results
None listed