Gastroesophageal reflux disease
Conditions
Interventions
Stretta Group
PECC Group:Endoscopic treatment
Sponsors
Inner Mongolia University of Science and Technology Baotou Medical College Second Affiliated Hospita
Eligibility
Sex/Gender
All
Age
40 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Clinical diagnosis (with heartburn, acid reflux symptoms); (2) 24h esophageal pH-impedance monitoring in accordance with Demeester score > 14.72, or pathological weak acid reflux or weak base reflux; (3) PPI-based After treatment for more than 2 months, the symptoms were not relieved or repeated after remission; (4) According to the classification of the valve, the endoscopic diagnosis was grade II, that is, the cardia was slack but the diagnostic criteria for esophageal hiatus were not reached.
Exclusion criteria
Exclusion criteria: (1) Patients with Barrett's esophagus or early cancer confirmed by pathological biopsy; (2) Patients who have undergone surgical treatment such as gastric folding surgery, patients whose normal physiological anatomy has been destroyed; (3) Esophageal hiatus hernia, ie LES-CD Separation > 2cm; (4) Patients with severe cardiopulmonary disease.Note: Reflux esophagitis is not included in the treatment, and drug treatment can be included in the study after mucosal healing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative; | — |
Countries
China
Contacts
Public ContactXian mei Meng
Inner Mongolia University of Science and Technology, Baotou Medical College Second Affiliated Hospital
Outcome results
None listed