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Observation of micro blood perfusion and vascular morphology in the posterior pole of high myopia and its relationship with complications of high myopia

Observation of micro blood perfusion and vascular morphology in the posterior pole of high myopia and its relationship with complications of high myopia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100043611
Enrollment
Unknown
Registered
2021-02-23
Start date
2021-03-01
Completion date
Unknown
Last updated
2021-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

high myopia

Interventions

Simple high myopia group vs. Pathological high myopia group:Nil

Sponsors

Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Simple high myopia group: standard constrain: 1. Agree to participate in this research; 2. Equivalent spherical lens power >= -6.00D, the refractive power remains stable in the past 1 year, no fundus complications; 3. The eye position is normal and the central fixation point is good; 4. No history of eye trauma or other eye diseases; 5. No history of serious systemic diseases such as nervous system and immune system; 6. Non-contact tonometer measures intraocular pressure 25; 8. The thickness of the retina and choroid has become thinner, and the scleral layer structure of the patient can be seen in the OCT image. (2) Pathological high myopia group: standard constrain: 1. Agree to participate in this research; 2. Equivalent spherical power >= -6.00D, myopia continued to deepen, or accompanied by one of the following fundus complications: fundus choroidal atrophy, retinal pigment epithelial atrophy, paint cracks, Fuch spots, macular hemorrhage, and choroidal neoplasia in the macular area Changes in blood vessels, macular hole, etc.; 3. The eye position is normal and the central fixation point is good; 4. No history of eye trauma or other eye diseases; 5. No history of serious systemic diseases such as nervous system and immune system; 6. Non-contact tonometer measures intraocular pressure 25; 8. The thickness of the retina and choroid has become thinner, and the scleral layer structure of the patient can be seen in the OCT image.

Exclusion criteria

Exclusion criteria: 1. During OCT and OCTA examinations, they cannot cooperate well due to incorrect eye position or poor fixation; 2. Diabetic high myopia caused by poor blood sugar control; 3. Incomplete medical records, other eye diseases or serious systemic diseases cannot be excluded.

Design outcomes

Primary

MeasureTime frame
choroidal thickness;retinal thickness;axial length;number of peforating scleral vessel;

Countries

China

Contacts

Public ContactXufang Sun

Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

sunxufang2016@163.com+86 83663410

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026