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Early clinical predictors of early neonatal sepsis

Clinical value of serum cholinesterase in neonatal early onset septicemia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100043610
Enrollment
Unknown
Registered
2021-02-23
Start date
2021-07-01
Completion date
Unknown
Last updated
2021-07-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neonatal early onset septicemia

Interventions

non critical group, critical group and extremely critical group:Nil

Sponsors

Affiliated Changzhou Children's Hospital of Nantong University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All neonatal EOS diagnoses were determined using the expert consensus on the diagnosis and treatment of neonatal sepsis (2019 Edition). A neonatal EOS suspected diagnosis included any of the following within 3 days of age: (a) abnormal clinical manifestations, (b) a mother with chorioamnionitis, or (c) premature rupture of membranes >= 18 hours. A neonatal EOS clinical diagnosis included clinical abnormalities with any of the following conditions: (a) two or more positive non-specific blood tests, (b) a cerebrospinal fluid test for suppurative meningitis changes, or (c) DNA of pathogenic bacteria detected in blood. A neonatal EOS definitive diagnosis included clinical manifestations, or a positive blood culture or cerebrospinal fluid (or other sterile cavity fluid) culture. Cases diagnosed by any of these diagnostic methods were included in this study.

Exclusion criteria

Exclusion criteria: Exclusion criteria included genetic metabolic diseases, malnutrition, and liver-based diseases.

Design outcomes

Primary

MeasureTime frame
serum cholinesterase,SChE;

Countries

China

Contacts

Public ContactZhang Qinfen

Affiliated Changzhou Children's Hospital of Nantong University

qfz2010@hotmail.com+86 13815059770

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026