neonatal early onset septicemia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All neonatal EOS diagnoses were determined using the expert consensus on the diagnosis and treatment of neonatal sepsis (2019 Edition). A neonatal EOS suspected diagnosis included any of the following within 3 days of age: (a) abnormal clinical manifestations, (b) a mother with chorioamnionitis, or (c) premature rupture of membranes >= 18 hours. A neonatal EOS clinical diagnosis included clinical abnormalities with any of the following conditions: (a) two or more positive non-specific blood tests, (b) a cerebrospinal fluid test for suppurative meningitis changes, or (c) DNA of pathogenic bacteria detected in blood. A neonatal EOS definitive diagnosis included clinical manifestations, or a positive blood culture or cerebrospinal fluid (or other sterile cavity fluid) culture. Cases diagnosed by any of these diagnostic methods were included in this study.
Exclusion criteria
Exclusion criteria: Exclusion criteria included genetic metabolic diseases, malnutrition, and liver-based diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum cholinesterase,SChE; | — |
Countries
China
Contacts
Affiliated Changzhou Children's Hospital of Nantong University