Carotid stenosis
Conditions
Interventions
SI Group:Sustained inflation (sustained manual inflation to a peak airway pressure of 30 cm H2O for 30 seconds)
IP Group:A stepwise increase in positive end-expiratory pressure to a peak airway pressure of 30 cm H2O for 30 seconds
Sponsors
Xuanwu Hospital of CCMU
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiologists (ASA) physical status I-III; 2. Aged >40 years old; 3. Suffering from Carotid stenosis and will be given an elective surgery; 4. Patients join in the research for voluntary.
Exclusion criteria
Exclusion criteria: 1. American Society of Anesthesiologists (ASA) physical status over ?; 2. Patients with severe hypertension (180/110mmhg), severe valvular disease and severe arrhythmia, Myocardial infarction occurred within three months; 3. Patients with severe COPD and asthma, pulmonary blisters, spontaneous pneumothorax, and the history of lobectomy; 4. Patients with severe heart and lung disease cannot tolerate this operation; 5. Patients refused or quitted the research; 6. Patients currently participating in other interventional studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Distribution of pulmonary ventilation (proportion of ventilation in each region of interest); | — |
Secondary
| Measure | Time frame |
|---|---|
| Age;Gender;Body Mass Index;Blood pressure;HR;Tidal volume;Peak airway pressure;ASA status;Complication of other systems;The operation side;PaO2;P?CO2;Mean velocity of blood flow in the middle cerebral artery;Regional cerebral oxygen saturation;Arterial pH;Arterial blood lactate; | — |
Countries
China
Contacts
Public ContactZHAO Lei
Xuanwu Hospital of CCMU
Outcome results
None listed