Parkinson Disease
Conditions
Interventions
Therapy Group:Cell Therapy
Sponsors
Xiang'an Hospital Affiliated to Xiamen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Selection criteria: Only those who meet all the following selected items can be enrolled in this experiment: 1. Primary Parkinson's patients who meet the diagnostic criteria of Parkinson's disease in China exclude other neurodegenerative diseases; 2. Male or female, aged 18-70 years; 3. After standardized drug treatment, there are sports complications and poor drug control; 4. The main organs function normally, that is, they meet the following standards: 5. Blood routine: HB = 60 g/L (no blood transfusion or erythropoietin (EPO) dependence within 14 days); ANC =1.5×109/L PLT =50×10*9/L 6. Blood biochemistry: TBIL < 1.5× ULN, ALT and AST < 2.5× ULN; 7.Cr=1.5×ULN or creatinine clearance rate (CCR) = 60 ml/min; 8. Urine protein in routine examination is less than 2+, or urine protein in 24 hours is less than 1g; 9. Coagulation function test is in normal range, INR and PT=1.5 times ULN; If the subject is receiving anticoagulant therapy, as long as PT is within the intended use range of anticoagulant drugs; 10. Doppler ultrasound evaluation: Left ventricular ejection fraction (LVEF) = the lower limit of normal value (50%).
Exclusion criteria
Exclusion criteria: Exclusion criteria (subjects with any of the following items will not be included in this study): 1. Those who are highly allergic or have a history of severe allergies; 2. Coagulation dysfunction; 3. Patients with malignant tumors; 4. Complicated with dysfunction of heart, lung, liver, kidney and other important organs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| UPDRS score; | — |
Contacts
Public ContactSong Yabin
Xiang'an Hospital Affiliated to Xiamen University
Outcome results
None listed