hyperuricemia and primary gout
Conditions
Interventions
Case series:No
Sponsors
Affiliated Hospital of Qiingdao University
Eligibility
Sex/Gender
All
Age
6 Years to 86 Years
Inclusion criteria
Inclusion criteria: (1) Definite diagnosis of hyperuricemia (serum uric acid >= 416µmol/L (7mg/dL)) or primary gout (meets the 2015 ACR/EULAR classification and diagnostic criteria for gout); (2) Patients aged 6-86 years; (3) Patients who voluntarily participate in and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with secondary gout (Gout Caused by potential diseases or drugs such as aspirin, cyclosporine, diuretics, etc.); (2) Pregnant or lactating women; (3) Patients with severe cardiovascular and cerebrovascular diseases, liver, kidney, malignant tumors, hematopoietic system and mental diseases. (4) Patients who voluntarily participate in and sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum uric acid;Metabolomics; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine;Blood biochemistry;Erythrocyte sedimentation rate;CRP;CA72-4;Urine routine;Urine PH;Ultrasound of urinary system;Joint ultrasound;Joint dual-energy CT;eGFR;The frequency of acute gout;Joint symptoms and signs;General symptoms and signs;Abdominal Doppler Ultrasound;ECG;Serum electrolytes;Tophi;Blood pressure;BMI;Waist circumference;Hips;Human leukocyte antigen B5801 gene detection;24-hour urine sample analysis;Joint X-ray;Stool routine;Intestinal flora detection;serum cytokines;cytokines in synovial fluid;Inbody body composition analysis;Quality of Life Assessment Scale;Vaccination against novel coronavirus (COVID-19); | — |
Countries
China
Contacts
Public ContactJie Lu
Qingdao University
Outcome results
None listed