Labor analgesia
Conditions
Interventions
Group 50: The infusion pump will deliver programmed intermittent epidural boluses at a 50-minute interval.
Sponsors
The First Affiliated Hospital of University of science and technology of China
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Healthy nulliparous women aged 20 to 40 years, classified as American Society of Anesthesiologists class II and III who had a singleton vertex presentation at 37–42 weeks gestation in active labor with a cervical dilation between 2 and 5cm as well as a baseline pain score >5 (NRS 0–10, 0 = no pain and 10 = the worst imaginable pain) at the time of request for epidural analgesia will be recruited.
Exclusion criteria
Exclusion criteria: Morbid obesity, pregnancy-related diseases (ie, gestational diabetes, gestational hypertension, cardiopulmonary dysfunction, preeclampsia), history of drug abuse, contraindications to neuraxial blocks, conditions that increase the risk of a cesarean delivery (ie, placenta previa, history of uterine anomaly, or surgery), receipt of parenteral opioids or sedatives in the previous 4 h before epidural analgesia, and known fetal abnormalities. Participants were also excluded from the analysis in the event of an inadvertent dural puncture using the epidural needle, when cerebrospinal fluid (CSF) could not be confirmed with the spinal needle while performing the dural puncture, patients who did not achieve NRS <=3/10 within 20 minutes after the completion of the loading dose, or if a delivery occurred within 1 hour after epidural catheter placement.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score;The level of sensory block; | — |
Contacts
Public ContactChristina Yang
Anhui Provincial Hospital
Outcome results
None listed