Changes of lactate dehydrogenase (LDH) in the cerebrospinal fluid and its value for evaluating the brain damage degree in the patient after craniocerebral operation

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100043551

Enrollment

Unknown

Registered

2021-02-21

Start date

2021-03-01

Completion date

Unknown

Last updated

2021-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

TBI

Interventions

simple TBI patients versus non-TBI trauma patients :no

Eligibility

Sex/Gender

All

Age

19 Years to 50 Years

Inclusion criteria

Inclusion criteria: Observation group (TBI patients) and control group (non TBI trauma patients); The inclusion criteria and severity (AIS and ISS scores) were as follows: 1. Subjects aged 19-50 years; 2. All patients were definitely diagnosed as traumatic brain injury; 3. Subjects who had performed at least one head CT examination after admission; 4. Subjects without severe thoracoabdominal injury; 5. Subjects without brain diseases (brain tumors, etc.); 6. According to AIS and ISS scores, they were divided into mild injury group and severe injury group.

Exclusion criteria

Exclusion criteria: 1. Patients with severe heart, liver and kidney dysfunction; 2. Patients with systemic infection; 3. Patients with mental history or unable to cooperate with treatment due to other reasons.

Design outcomes

Primary

Measure	Time frame
CSF-LDH;	—

Countries

China

Contacts

Public ContactZhuo Liyuan

Longgang Central Hospital

706921091@qq.com+86 15914033363

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026