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Antihypertensive effect of sacubitril/valsartan in peritoneal dialysis patients complicated with refractory hypertension

Antihypertensive effect of sacubitril/valsartan in peritoneal dialysis patients complicated with refractory hypertension

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100043544
Enrollment
Unknown
Registered
2021-02-21
Start date
2021-03-01
Completion date
Unknown
Last updated
2021-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refractory hypertension in maintenance peritoneal dialysis

Interventions

Sponsors

Department of Nephrology, General Hospital of Ningxia Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The age is over 18 years old; 2. Regular peritoneal dialysis for more than 3 months; 3. Meet the diagnostic criteria of refractory hypertension; 4. Willing to participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Take combined dialysis treatment; 2. Severe heart failure (NYHA grade IV); 3. People who are allergic to the active ingredients of sacubitril/valsartan (Sacubitril, Valsartan) or any auxiliary materials. 4. Acute complications (peritonitis, abdominal infection and other acute infections, etc.) occurred in recent 1 month; 5. Diagnosis of malignant tumor; 6. Patients with angioedema; 7. Mental disorders cannot cooperate; 8. It is impossible to measure blood pressure through upper limbs.

Design outcomes

Primary

MeasureTime frame
24 hour ambulatory blood pressure;

Countries

China

Contacts

Public ContactTianna

Department of Nephrology, General Hospital of Ningxia Medical University

snowwife@163.com18095173735

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026