Refractory hypertension in maintenance peritoneal dialysis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The age is over 18 years old; 2. Regular peritoneal dialysis for more than 3 months; 3. Meet the diagnostic criteria of refractory hypertension; 4. Willing to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Take combined dialysis treatment; 2. Severe heart failure (NYHA grade IV); 3. People who are allergic to the active ingredients of sacubitril/valsartan (Sacubitril, Valsartan) or any auxiliary materials. 4. Acute complications (peritonitis, abdominal infection and other acute infections, etc.) occurred in recent 1 month; 5. Diagnosis of malignant tumor; 6. Patients with angioedema; 7. Mental disorders cannot cooperate; 8. It is impossible to measure blood pressure through upper limbs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24 hour ambulatory blood pressure; | — |
Countries
China
Contacts
Department of Nephrology, General Hospital of Ningxia Medical University