inflammatory bowel disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. First diagnosed as Crohn's disease; 2. under the mild to moderate activity period; 3. Aged >= 18 and <= 75 years; 4. according to the clinician's judgment, azathioprine is proposed to be used as the treatment of induced remission; 5. with the educational level of primary school or above, who can understand the content of this study; 6. voluntarily participate in the study, and can receive the randomization, as well as sign informed consent; 7. have smartphone and network and be able to participate in online follow-up.
Exclusion criteria
Exclusion criteria: 1. Severe IBD patients requiring close monitoring; 2. with previous usage of corticosteroids, immunomodulators and biological agents; 3. with possible/planned surgical intervention in three to six months; 4. with short bowel syndrome, experienced more than two bowel operations, fistula surgery, bag storage surgery or large-scale bowel surgery; 5. with abdominal abscess infection, fistula, tumor history; 6. combined with severe primary disease including cardiovascular and cerebrovascular, liver, kidney, etc; 7. women who are pregnant; 8. those who are not suitable for inclusion judged by researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Crohn's disease activity index, CDAI;HRQOL;rate of clinical remission; | — |
Secondary
| Measure | Time frame |
|---|---|
| C-reactive proteins;blood routine examination;blood biochemical indexes;reporting rate of adverse drug reactions;Incidence of severe adverse drug reactions;Compliance;usability;cost; | — |
Countries
China
Contacts
The Affiliated Wuxi People's Hospital, Nanjing Medical University