Predicting fluid responsiveness in patients on veno-arterial extracorporeal membrane oxygenation by using heart-lung interaction mechanism

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100043538

Enrollment

Unknown

Registered

2021-02-21

Start date

2021-04-01

Completion date

Unknown

Last updated

2021-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

shock

Interventions

Gold Standard:Fluid responsiveness was defned as a VTI or Vpeak increase of 15% or more after fluid challenging.

Index test:Fluid&#32

challenging,&#32

lung&#32

recruitment&#32

maneuver,&#32

end-expiratory&#32

occlusion.

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Adult patients with hypotension or hypoperfusion (oliguria, skin moltting, hyperlacticemia, metabolic acidosis) fluid challenging is necessary judged by attending physician.

Exclusion criteria

Exclusion criteria: Aged < 18 years, pregnancy, pulse pressure < 15mmHg, pneumothorax, mediastinal emphesema, high intracranial pressure, brain death, unsatisfactory cardiac echogenicity via TTE (an inability to correctly align the Doppler beam to generate reliable VTI and Vpeak measurements at the left ventricular outfow tract [LVOT]).

Design outcomes

Primary

Measure	Time frame
r;VTI;Vpeak;ETCO2;ScvO2;	—

Secondary

Measure	Time frame
SAP;DAP;MAP;PP;	—

Countries

China

Contacts

Public ContactChen Xufeng

The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital

cxfyx@njmu.edu.cn+86 13915906015

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026