ED50 of propofol for insertion of laryngeal mask airway

Status

Recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100043532

Enrollment

Unknown

Registered

2021-02-21

Start date

2021-03-01

Completion date

Unknown

Last updated

2021-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laryngeal mask airway

Interventions

one:up-and-down rule designed by Dixon and Massey

Eligibility

Sex/Gender

All

Age

2 Years to 8 Years

Inclusion criteria

Inclusion criteria: (1) Ages 2-8 years. (2) General anesthesia was performed electively (laryngeal mask). (3) No abnormal anatomical structure of oropharyngeal cavity was observed. (4) No history of sensation within two weeks. (5) No previous history of systemic disease. (6) Get permission from parents or guardians (sign informed consent).

Exclusion criteria

Exclusion criteria: (1) ASA grading >= 2. (2) Abnormal liver function and history of other systemic diseases. (3) Are currently using a sedative pump (e.g., propofol, morphine, fentanyl, midazolam, dexmedetomidine, ketamine) or have recently used a sedative pump (withdrawal time < 24 hours).

Design outcomes

Primary

Measure	Time frame
ED50 of propofol;	—

Countries

China

Contacts

Public ContactYang Shen

Shanghai Children's Medical Center

rdshenyang@163.com+86 18201806327

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026