procedure sedation
Conditions
Interventions
High-dose remimazolam non-elderly group:Sufentanil 0.08ug/kg+ Remimazolam 0.08mg/kg
Medium-dose remimazolam non-elderly group:Sufentanil 0.08ug/kg+ Remimazolam 0.06mg/kg
Control non-elderly group:Sufentanil 0.08ug/kg
Middle-dose remimazolam elderly group:Sufentanil 0.08ug/kg+ Remimazolam 0.06mg/kg
Low-dose remimazolam elderly group:Sufentanil 0.08ug/kg+ Remimazolam 0.04mg/kg
Control elderly group:Sufentanil 0.08ug/kg
Sponsors
Department of Anesthesiology and Critical Care Medicine, Peking University First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Participants selected for this study must meet all of the following conditions: 1. Aged 18-85 years; 2. Patients who intend to undergo nerve block operations; 3. Agree to participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria are listed as follows: 1. Chronic pain and opioid dependence (taking opioids regularly in the past 3 months); 2. Those who cannot communicate due to delirium, dementia, central and/or peripheral nervous system diseases, language disorders or other end-stage diseases before surgery; 3. Those who are allergic to benzodiazepines; 4. Preoperative ASA classification > IV.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the rate of successful sedation; | — |
Secondary
| Measure | Time frame |
|---|---|
| MOAA/S score;Blood pressure;pain score;onset and recovery time;procedure duration;satisfaction score;BIS;Adverse events; | — |
Countries
China
Contacts
Public ContactLi Xue
Department of Anesthesiology and Critical Care Medicine, Peking University First Hospital
Outcome results
None listed