Immune thrombocytopenia
Conditions
Interventions
Healthy control group:Nil
Sponsors
Xiyuan Hospital, Chinese Academy of traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. The patients with definite diagnosis of ITP, whose course of disease is more than 12 months, aged 18-75 years, 80 x 10^9 /L > PLT >10 x 10 ^ 9 / L or bleeding symptoms; 2. Patients with purpura of spleen and kidney yang deficiency syndrome of TCM; 3. Patients with informed consent, voluntary participation and regular medication. 4. Healthy people with informed consent, voluntary participation and age of 18-60.
Exclusion criteria
Exclusion criteria: 1. Patients who received high-dose glucocorticoid pulse therapy within 3 months before treatment. 2. The subjects who received other treatments except hormone within 30 days before treatment, or participated in other clinical studies, which may have an impact on the observation indexes of curative effect. 3. Patients with severe immune deficiency or severe gastrointestinal and / or visceral bleeding. 4. Patients with severe heart, liver and kidney dysfunction: serum creatinine is higher than the upper limit of normal value; Alanine aminotransferase, aspartate aminotransferase and bilirubin were 2 times higher than normal; NYHA grade >= grade II; Or mental illness patients. 5. Pregnant, lactating women or subjects with allergic constitution.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Platelet count;Immune related cytokines;T/B lymphocyte subsets; | — |
Countries
China
Contacts
Public ContactXu Yonggang
Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine
Outcome results
None listed