the chronic fatigue syndrome
Conditions
Interventions
CFS group:Taijiquan Training
Healthy control group:Taijiquan Training
Sponsors
Dongzhimen Hospital, Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: CFS group:1 1) Corresponded to CFS diagnostic criteria, and FS-14 scale >= 7 points; 2) Aged 25-65, male or female, right-handed; 3) The course of disease is longer than 6 months; 4) Chronic fatigue state cannot be explained by current illness; 5) No previous Tai Chi Chuan practice history; 6) Can answer and fill in the questionnaire normally, with good compliance; 7) Not taking psychotropic drugs in the past month; 8) No metal in body, no contraindication to nuclear magnetic examination; 9) Signed the informed consent.Note:Patients who do not meet any of the above criteria will not be included. Healthy control group: 1) The gender and age of patients were matched with CFS group,right-handed; 2) Age between 25 and 65, male and female; 3) Those who have been confirmed to be in the range of physical health by physical examination have no organic or significant functional diseases, and have no previous practice history of Tai Chi Chuan; 4) No family genetic history of mental or nervous system; 5) Have not participated in any research similar to this study; 6) No physical abnormalities (such as cold,headache,cough,etc.)during the experiment; 7) Have not taken any stimulant drugs in the past 2 months; 8) No metal implants in body, no contraindication of functional magnetic resonance testing; 9) The subject signs the informed consent and volunteers to participate in this study. Note:those who do not conform to any of the above items will not be included.
Exclusion criteria
Exclusion criteria: CFS group: 1)The primary disease itself may cause chronic fatigue,such as hypothyroidism,hepatitis B or C virus infection; 2)Chronic fatigue caused by drug side effects; 3)Previous diagnosis of mood disorders and various mental disorders,such as paranoia, anorexia nervosa; 4)Suffering from serious heart,kidney,lung,liver,brain and other major diseases,or severe abnormal liver and kidney functions; 5)Severe obesity,body mass index =[weight(kg)/height^2(m)]>45; 6)Patients taking vasodilators in the last two weeks; 7)Pregnant women, lactating women and menstruating women; 8)Those who cannot understand and cooperate with MRI examination or have claustrophobia and other contraindication in MRI examination; 9)Severe skull anatomical asymmetry or definite lesions are found in MRI scan; 10)Those who had participated in a similar neuroimaging study within one month.Note:those who meet any of the above conditions will be excluded. Healthy control group: 1)Menstrual women, pregnant women and lactating women; 2)Subjects with claustrophobia or other contraindication to MRI; 3)Severe skull anatomical asymmetry or definite lesions were found on MRI scan; 4)Related diseases of nervous system dysfunction; 5)Can't cooperate to complete the research. Note:those who meet any of the above conditions will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FS-14; | — |
Secondary
| Measure | Time frame |
|---|---|
| MPQ;PSQI;HAMD;SF-36; | — |
Countries
China
Contacts
Public ContactKuangshi Li
Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine
Outcome results
None listed