critical illness
Conditions
Interventions
Infected patients admitted to ICU and receiving intravenous antibiotics vs. Healthy individuals who did not receive antibiotic treatment.:Nil
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The case group and control group designed for this project are: 1. Infected patients admitted to ICU and receiving intravenous antibiotics; 2. Healthy individuals who did not receive antibiotic treatment. The inclusion criteria for the case group are as follows: (1) Patients who have been in ICU for more than 1 week and have not been hospitalized within half a year prior to this admission (aged over 18 years); (2) Intravenous antibiotics have been given for more than 1 week, and there is no oral and nasogastric tube antibiotic treatment. (3)No antibiotics (oral, intravenous, nasogastric tube, etc.) have been used in the six months before this study. The inclusion criteria of the control group are as follows: (1) In healthy individuals aged 18 years or above, no antibiotics have been used within 6 months before the study; (2) Normal blood glucose and body mass index.
Exclusion criteria
Exclusion criteria: Exclusion criteria for the case group were as follows: (1) Patients using hormone drugs; (2) Patients receiving radiotherapy and chemotherapy; (3) patients taking probiotics; Exclusion criteria for the control group were as follows: (1) People suffering from chronic metabolic diseases, chronic inflammation, autoimmune diseases, thyroid diseases and mental diseases; (2) Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiota; | — |
Countries
China
Contacts
Public ContactZemao Xing
Shenzhen Second People's Hospital
Outcome results
None listed