Adenomyosis
Conditions
Interventions
experimental group:HIFU ablation combined with TBEA
control group:HIFU ablation
Sponsors
Mianyang Central Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Patients with diffuse adenomyosis and abnormal uterine bleeding; 2. Patients who are unable to tolerate or fail to receive drug treatment (including LNG-IUS treatment failure); 3. Subjects who required to keep uterus and had no fertility requirements; 4. Subjects with unilateral myometrial thickening >= 30mm indicated by transvaginal ultrasound; 5. For the subjects with good acoustic channel located by HIFU before operation, the focus moving area can cover the scope of the lesions to be treated.
Exclusion criteria
Exclusion criteria: 1. Patients with fertility requirements. 2. Patients with severe anteflexion and retroflexion of uterus, genital tract deformity, or adhesion of cervix and uterine cavity, intrauterine mediastinum. 3. Patients who have undergone endometrial resection or ablation, or who have undergone HIFU ablation. 4. Patients with non benign uterine diseases. 5. Subjects with pregnancy or suspected pregnancy. 6. Patients with severe internal and external diseases can not tolerate HIFU or TBEA. 7. Patients who received other treatments (including GnRHa, gestrinone, uterine artery embolization, etc.) in the past three months. 8. Subjects who can not cooperate with HIFU treatment and complete the follow-up after operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PBAC; | — |
Secondary
| Measure | Time frame |
|---|---|
| dysmenorrhea; | — |
Countries
China
Contacts
Public ContactZhang Yong
Department of Obstetrics & Gynecology, Mianyang Central Hospital
Outcome results
None listed