Colorectal Neoplasms
Conditions
Interventions
experiment group:L-Arabinose syrup
control group:PEG-ELP (IV)
Sponsors
The Seventh Medical Center of Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Outpatients aged 18–75 years undergoing a colonoscopy who had provided written informed consent, and without blood-activating drugs for 5-7 days before examination were eligible for participation in the study.
Exclusion criteria
Exclusion criteria: 1. Bowel preparation within 14 days; 2. previous significant abdominal surgeries; 3. dysphagia, compromised swallowing reflex, or mental status; 4. significant gastroparesis or gastric outlet obstruction or ileus; 5. known or suspected bowel obstruction or perforation; 6. severe chronic renal failure (creatinine clearance170 mm Hg, diastolic blood pressure>100 mm Hg); 9. suffering from cardiovascular and cerebrovascular diseases or previous history of cardiovascular and cerebrovascular accidents; 10. severe constipation; 11. severe acute inflammatory bowel disease or toxic colitis or megacolon; 12. dehydration, disturbance of electrolytes, or hemodynamically unstable; 13. pregnancy or lactation; 14. allergy to the preparation components; 15. use of tricyclic antidepressants or narcotics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the rate of adequate bowel preparation based on BBPS scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| comfort and tolerance evaluation of the two groups of subjects;willingness to repeat bowel preparation;cleansing quality for each segment of the colon (right, transverse, and left colon segments);caecal intubation rate;adenoma detection rate;caecal intubation time;flushing water consumption during operation;electrolyte disturbance;changes in liver and kidney function;the incidence of adverse reactions during bowel preparation; | — |
Countries
China
Contacts
Public ContactXin Wang
The Seventh Medical Center of Chinese PLA General Hospital
Outcome results
None listed