Functional near-infrared spectroscopy study of depression

Using functional near- infrared spectroscopy to explore the changes of brain activation in patients with depression during cognitive task

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100043432

Enrollment

Unknown

Registered

2021-02-17

Start date

2021-03-01

Completion date

Unknown

Last updated

2021-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depression

Interventions

depression group vs healthy control group:Nil

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-60 years, right handedness; 2. meet the diagnostic and Statistical Manual of mental disorders, Fifth Edition (dsm-5) depression diagnostic criteria; 3. first episode or relapse; 4. 24 item Hamilton Depression Scale (HAMD-24) > 20 points; 5. no previous hypomania or manic episode.

Exclusion criteria

Exclusion criteria: 1. History of brain injury or other organic brain diseases; 2. current patients with alcohol or other substance dependence; 3. history of major physical diseases (for example, cardiovascular diseases, hepatitis, major respiratory diseases, thyroid diseases and diabetes mellitus); 4. pregnant women and lactating women; 5. patients who have received modified electroconvulsive therapy in the past six months; 6. patients who can not complete cognitive tasks or fNIRS detection.

Design outcomes

Primary

Measure	Time frame
oxy-Hb;	—

Countries

China

Contacts

Public ContactJuan Wang

The Second Affiliated Hospital of Xinxiang Medical University

wjwgd8281@sina.com+86 13598749375

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026