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The effect of tumor microbiome on nasopharyngeal carcinoma and its immune microenvironment: an exploratory study

The effect of tumor microbiome on nasopharyngeal carcinoma and its immune microenvironment: an exploratory study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100043414
Enrollment
Unknown
Registered
2021-02-15
Start date
2021-02-20
Completion date
Unknown
Last updated
2021-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nasopharyngeal carcinoma

Interventions

Nasopharyngeal carcinoma group:Nil
Benign nasopharyngeal nodules group:Nil

Sponsors

The Fifth Affiliated Hospital of Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients with nasopharyngeal carcinoma or benign nasopharyngeal nodules (non nasopharyngeal carcinoma) confirmed by histology or cytology; 2. Over 18 years old and under 75 years old; 3. ECOG:0-2 points; 4. According to RECIST 1.1, there is at least one measurable lesion in patients with nasopharyngeal carcinoma; 5. Expected survival >= 6 months.

Exclusion criteria

Exclusion criteria: 1. The patient with other uncontrollable diseases or a history of other malignant tumors within 5 years; 2. Contraindications to chemotherapy and radiotherapy; 3. Patients with nasopharyngeal carcinoma had systemic active infection before diagnosis; 4. Pitients with a history of taking antibiotics within half a month before diagnosis; 5. The researchers determined the patients not suitable for inclusion.

Design outcomes

Primary

MeasureTime frame
Bacterial abundance;

Countries

China

Contacts

Public ContactZhigang Liu

The Fifth Affiliated Hospital of Sun Yat-Sen University

zhigangliu1983@hotmail.com+86 18627585860

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026