anesthesia for bronchoscopy
Conditions
Interventions
R group:Remifentanil TCI
S group:Sufentanil TCI
Sponsors
Shanghai Pulmonary Hospital, Tongji University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients with severe tracheal stenosis Myer-cotton gradation 2-4; 2. Undergoing fiberoptic bronchoscopy; 3. Aged 18-65 years; 4. ASA I-III; 5. BMI18.5~30 kg/m2.
Exclusion criteria
Exclusion criteria: 1) Patients with chronic pain who have used analgesics, psychotropic drugs (including opioids, NSAIDs, sedatives, and antidepressants), alcohol abusers for a long time. 2) Liver and kidney functions (ALT, AST, BUN, Cr) are abnormally increased before surgery, which is more than 1.5 times the normal value. 3) History of abnormal surgical anesthesia recovery. 4) In the past or at present, patients had hypertension which could not be controlled by drugs, or systolic blood pressure >= 170 mmHg or diastolic blood pressure >= 100 mmHg during the screening period. 5) Suffer from esophageal reflux disease. 6) Sedatives, antiemetics, and antipruritic drugs were used 24 hours before the operation. 7) Expected to be difficult intubation. 8) History of opioid allergy. 9) Take monoamine oxidase inhibitors or antidepressants within 15 days. 10) Shock patients. 11) Patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). 12) Pregnant or parturient. 13)Patients who do not sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of hypoxemia;; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cough score;the alteration of HR and BP;OAA/S score and Ramsay score;Fully awake time;The degree and incidence of nausea and vomiting;Questionnaire on satisfaction of subjects and anesthesiologists; | — |
Countries
China
Contacts
Public ContactLiu Jianming
Shanghai Pulmonary Hospital, Tongji University
Outcome results
None listed