Tinnitus
Conditions
Interventions
Experimental Group:Oral quinadol 80mg, TID
control group:Oral quinadol 80mg, TID
Sponsors
The Second People's Hospital of Shenzhen
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Aged 18 to 65 years; 2) The first episode of unilateral idiopathic sudden deafness, PTA decreased >= 30dB in 3 consecutive frequencies at least compared with the contralateral ear; 3) Normal hearing in the contralateral ear, or age-appropriate hearing loss; 4) The course of sudden deafness is less than 3 months; 5) The THI score of new tinnitus on the same side after sudden deafness was higher than Grade 2 (including Grade 2), that is, 18 points or above; 6) No previous bilateral history of tinnitus; 7) No previous history of bilateral ear diseases affecting hearing; 8) Signed the informed consent; 9) Follow-up can be maintained.
Exclusion criteria
Exclusion criteria: 1) Sudden deafness of any definite cause; 2) Other oral drugs for improving microcirculation had been used or were being used within 3 months before enrollment, including but not limited to: Ginkgo biloba leaves, Ginkgo biloba extracts drops, Xuesetone, Lumbrokinase, prostatin tablets, etc 3) Patients with severe heart disease, cerebral infarction, cerebral hemorrhage, poorly controlled hypertension, abnormal coagulation, malignant disease, heart failure, arrhythmia, hemodialysis, HBV, HCV, dementia and other serious diseases; 4) Patients with hyperlactic disease, methanol addiction, poor tolerance of fructose sorbitol and 1,6 diphosphate fructosase deficiency; 5) Women who are pregnant or preparing to become pregnant within 12 months; 6) People with previous definite diagnosis of depression, anxiety or mental disorder; 7) Past immune-related diseases with clear diagnosis; 8) The clinical examination data cannot be kept completely;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tinnitus VAS score;Absolute change in tinnitus THI score; | — |
Countries
China
Contacts
Public ContactYu Yanping
The Second People's Hospital of Shenzhen
Outcome results
None listed