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A novel substrate-inspired Fluorescence-based albumin detection improves the diagnosis of clinical outcomes in hemodialysis patients receiving a nursing nutrition intervention

dietary intervention on hemodialysis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100043341
Enrollment
Unknown
Registered
2021-02-11
Start date
2019-01-01
Completion date
Unknown
Last updated
2021-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

kidney disease

Interventions

experimental group:nursing nutritional supplementation

Sponsors

The First Affiliated Hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
36 Years to 59 Years

Inclusion criteria

Inclusion criteria: The patients were 18-60 years of age, underwent maintenance hemodialysis for at least 6 months and had mean albumin <3.5 g/dL for over 3 months and had kidney failure, which was confirmed using the values of estimated glomerular filtration rate (eGFR) less than 15 mL/min/1.73 m2.

Exclusion criteria

Exclusion criteria: Hepatic insufficiency was confirmed by using plasma levels of Aspartate aminotransferase (AST) and alanine aminotransferase (ALT), which were over 2 times of the upper limit of normal range; drug and alcohol abuse were found. Acute infection was detected. The women were excluded during pregnancy and lactation. Chronic kidney disease (CKD) and life-threatening complications were caused by dialysis. Kidney transplantation was performed within 3 months, and the expected survival time would be <= 1 year.

Design outcomes

Primary

MeasureTime frame
fluorescence-based plasma albumin;

Countries

China

Contacts

Public ContactLei You

The First Affiliated Hospital of Dalian Medical University

youleiyl@126.com+86 18098871136

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026