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Effects of different anesthesia management methods on perioperative intraocular pressure changes of patients undergoing robot-assisted laparoscopic radical prostatectomy

Effects of different anesthesia management methods on perioperative intraocular pressure changes of patients undergoing robot-assisted laparoscopic radical prostatectomy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100043330
Enrollment
Unknown
Registered
2021-02-10
Start date
2021-02-22
Completion date
Unknown
Last updated
2021-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostatic cancer

Interventions

Group D:Total intravenous anesthesia,no use of dexmedetomidine and no use of deep versus moderate neuromuscular blockade
Group A:Total intravenous anesthesia,dexmedetomidine and deep versus moderate neuromuscular blockade
Group B:Static inhalation combined anesthesia,no use of dexmedetomidine and deep versus moderate neuromuscular blockade
Group C:Static inhalation combined anesthesia,dexmedetomidine and no use of deep versus moderate neuromuscular blockade

Sponsors

Peking University First Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Subjects aged >= 50 and <= 80 years; 2. Subjects who plan to undergo robot assisted laparoscopic radical prostatectomy.

Exclusion criteria

Exclusion criteria: Those with one of the following conditions were not included in this study: 1. Subjects who refused to participate in this experiment; 2. Subjects with body mass index (BMI) > 30kg / m2; 3. Subjects with ASA grade > III; 4. Subjects with severe uncontrolled hypertension (SBP > 180mmhg or DBP > 110mmhg); 5. Subjects with previous eye diseases (diabetic retinopathy, glaucoma, retinal detachment, cataract, visual impairment) and previous ophthalmic surgery history; 6. Subjects with LVEF < 30% before operation, or patients with sick sinus syndrome, severe sinus bradycardia (heart rate < 50 beats / min), degree II or above atrioventricular block without pacemaker implantation.

Design outcomes

Primary

MeasureTime frame
Intraocular pressure;

Secondary

MeasureTime frame
Optic nerve sheath diameter;

Countries

China

Contacts

Public ContactZhang Hong

Peking University First Hospital

zhanghong40@hotmail.com+86 13910104660

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026