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Application of Urine DNA Point Mutation, Methylation, Copy Number Variation in Repeated Transurethral Resection of Bladder Cancer

Application of Urine DNA Point Mutation, Methylation, Copy Number Variation in Repeated Transurethral Resection of Bladder Cancer

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100043328
Enrollment
Unknown
Registered
2021-02-10
Start date
2021-02-01
Completion date
Unknown
Last updated
2021-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder cancer

Interventions

Gold Standard:Cystoscope and related pathological diagnosis.
Mutation?Methylation?Copy&#32
Variation.

Sponsors

Department of Urology, The Third Xiangya Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.Patients were pathologically diagnosed with urothelial carcinoma and required repeated transurethral resection, aged >= 18 years; 2.The clinical samples of each clinical trial object should be fresh and sufficient (Urine sample volume should be at least 40 ml); 3.All samples are from outpatient or inpatient specimens of clinical hospitals, and all samples must have clinical diagnosis or pathological diagnosis; 4.All samples should have corresponding basic clinical information, including sample ID number (outpatient number, medical record number, contact information and hospital number), gender, age, smoking history, chemical exposure history, family history of bladder cancer and clinical diagnosis information.

Exclusion criteria

Exclusion criteria: 1. Sample number (medical record number or hospital number, etc.), gender, age, clinical diagnosis and other information missing; 2. Samples are not fresh; 3. Samples are insufficient in quantity or abnormal in quality (Urine sample volume < 40 ml); 4. The concentration(5ng/µL of urine sample is not satisfactory; 5. The appearance color of urine samples was inconsistent or may be confused from 4 tubes.

Design outcomes

Primary

MeasureTime frame
Urinalysis;DNA Point Mutation;Methylation;Copy Number Variation;

Countries

China

Contacts

Public ContactLong Wang

Department of Urology, Xiangya Third Hospital of Central South University

doctorwanglong@163.com+86 13873151645

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026