Dysmenorrhea
Conditions
Interventions
Didrogesterone treatment group:10 mg of dydrogesterone was given orally twice a day from the 5th day to the 25th day of the menstrual cycle for 3 menstrual cycles.
Cassia zhiporing capsule treatment group:0.93 g of Guizhiporing Capsules was given orally ter in die while menstrual bleeding stops continuously to the 2th day of the next menstrual cycle for 3 menst
Sponsors
Guangdong Provincial Maternal and Child Health Hospital affiliated to Guangzhou Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Dysmenorrhea occurred on the 1st-5th day of menstruation or the 1st day before menstruation and met the following conditions: 1. Subjects aged 18-45 years; 2. Subjects who did not use hormonal and endocrine drugs within 3 months before the treatment had no history of using sedatives or analgesics in the first month; 3. The subjects who are willing and able to comply with the study protocol have the ability to clearly judge the pain intensity; 4. All patients with dysmenorrhea secondary to endometriosis have no operation indication or refuse operation treatment, and strongly demand drug treatment for pain.
Exclusion criteria
Exclusion criteria: 1. Patients with severe liver and kidney diseases; 2. Patients allergic to any component of the study drug; 3. Patients with severe cardiovascular disease; 4. Patients with porphyria; 5. Patients with hormone dependent tumor; 6. Patients with meningioma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| the Short Form Health Survey (SF-36);Cox Menstrual Symptom Scale;Simplified McGill Pain Questionnaire;menstruations; | — |
Countries
China
Contacts
Public ContactLi Li
Guangdong maternal and Child Health Hospital
Outcome results
None listed