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Study on The Optimal Dose and Safety of Mivacurium Chloride in Laparoscopic Cholecystectomy

Study on The Optimal Dose and Safety of Mivacurium Chloride in Laparoscopic Cholecystectomy

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100043298
Enrollment
Unknown
Registered
2021-02-09
Start date
2021-03-01
Completion date
Unknown
Last updated
2021-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cholecystitis

Interventions

case series:Nil

Sponsors

Zhongshan Hospital Affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Sign a written informed consent form. 2. Consecutive patients undergoing laparoscopic cholecystectomy under general anesthesia. 3. The age is 18 to 65 years old. 4. Body mass index (BMI) 18~30kg/m2. 5. ASA I~II patients.

Exclusion criteria

Exclusion criteria: 1. Patients with asthma, neuromuscular diseases and severe electrolyte acid-base disturbance. 2. BMI > 30kg/m2 or 180 mmHg or diastolic blood pressure > 110 mmHg. 4. Those who have taken drugs that affect neuromuscular function within 48 hours before operation. 5. Participated in other drug clinical researchers in the previous 30 days. 6. Patients who are known to be allergic to micuronium chloride or rocuronium. 7. Pregnant or lactating women. 8. Patients with creatinine clearance 3 times the upper limit of normal value. 10. Serum albumin < 30g/L. 11. Patients with difficult airway who cannot be ventilated with mask. 12. Patients with known or suspected atypical plasma cholinesterase gene homozygote and plasma cholinesterase decrease. 13. The researchers believe that there are other situations that are not suitable for selection.

Design outcomes

Primary

MeasureTime frame
muscle relaxant;

Countries

China

Contacts

Public ContactZhang Xiaoguang

Department of Anesthesiology, Zhongshan Hospital Affiliated to Fudan University

zhang.xiaoguang@zs-hospital.sh.cn+86 13641995773

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026