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Establishment and validation of a risk prediction model for myasthenia crisis after thymectomy in patients with myasthenia gravis: a multicenter, prospective cohort study

Establishment and validation of a risk prediction model for myasthenia crisis after thymectomy in patients with myasthenia gravis: a multicenter, prospective cohort study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100043284
Enrollment
Unknown
Registered
2021-02-09
Start date
2021-03-01
Completion date
Unknown
Last updated
2021-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myasthenia gravis

Interventions

Patients with myasthenia gravis undergoing thymectomy:Nil

Sponsors

Department of Neurology, The Second Affiliated Hospital of Air Force Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients who have been diagnosed with myasthenia gravis (MG) as assessed by neurologists in this center or other top-tier hospitals and meet the diagnostic criteria of the 2015 Chinese Myasthenia Gravis Guidelines; 2. Thymus imaging (CT or MR) clearly combined with thymic abnormalities (thymic hyperplasia or thymoma); 3. From January 2021 to December 2022, received expanded thymectomy in the Thoracic Surgery of the Research Center; 4. Subjects voluntarily join the study, agree to collect relevant information including thymus pathology information, and sign an informed consent form (patients under the age of 18 are signed by their legal representatives).

Exclusion criteria

Exclusion criteria: 1. Accompanied by serious underlying diseases, such as liver and kidney failure, heart failure, etc.; 2. Patients with other systemic tumors; 3. Mental illness affects prognosis assessment; 4. According to the judgment of the investigator, there are other patients with accompanying diseases that seriously endanger the safety of the patient or affect the completion of the study; 5. The investigator assesses those who are expected to have poor compliance.

Design outcomes

Primary

MeasureTime frame
Masthenia Crsis;

Countries

China

Contacts

Public ContactChangTing

The Second Affiliated Hospital of Air Force Medical University

changting1981@163.com+86 29-84778845

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026