Chronic otitis media
Conditions
Interventions
experimental group:Tympanum filling with gelatin sponge mixed with batroxase injection
control group:Tympanum filling with gelatin sponge mixed with dexamethasone injection
Sponsors
The First Affiliated Hospital of Air Force Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18-60 years; 2) Consistent with the diagnosis of chronic suppurative otitis media or cholestatoma of the middle ear, intraoperative mucosal defect or lesion of the lateral wall of the inner tympanic chamber was confirmed; 3) stapes or stapes floor (or processing) good mobility, type II or type III tympanoplasty. 4) The result of pure tone audiometry was conductive hearing loss or mixed hearing loss (mean bone conductance = 30dB.
Exclusion criteria
Exclusion criteria: 1) A history of ear surgery or trauma; 2) Patients undergoing other types of tympanoplasty, such as upper tympanoplasty and open tympanoplasty; 3) congenital diseases that affect middle ear function such as cleft palate; 4) Preoperative fibrinogen was <1.0g/L; 5) Those who cannot recheck as required.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| typanic canvity adhension;Tympanic membrane healed;hearing improvement; | — |
Countries
China
Contacts
Public ContactChen yang
Outcome results
None listed