Experimental study on treatment of dry eye in mice with exosomes from human cord blood

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100043255

Enrollment

Unknown

Registered

2021-02-09

Start date

2021-03-15

Completion date

Unknown

Last updated

2021-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye disease

Interventions

Normal group:PBS

Model group:Exosomes

Eligibility

Sex/Gender

Female

Age

20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Healthy pregnant women, 20-35 years old, Han nationality, full-term delivery.

Exclusion criteria

Exclusion criteria: Patients with any of the following cannot be included in this study: 1. Patients who have been or are receiving anticoagulant therapy or coagulopathy, including heparin, heparin analogs, aspirin therapy or known peripheral vein, pulmonary coagulation disorders; 2. Suffer from pregnancy complications or infectious diseases; 3. People with a history of smoking; 4. Drug abusers.

Design outcomes

Primary

Measure	Time frame
Tear break-up time;Schiermer test;Meibomian glands;Number of goblet cells;Expression of TNF-a, IL-1ß, TGF-ß and GM-CSF;	—

Countries

China

Contacts

Public ContactXiao Xianghua

Xi'an NO.1 Hospital

xianghuaxiao@yeah.net+86 18291939226

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026