Remifentanil-induced hyperalgesia
Conditions
Interventions
Observation Group:saline solution
Group DN:Dexmedetomidine+Nalbuphine
Sponsors
Department of Anesthesiology, Wuhu Second Peoples Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.ASA I-II objects, 2. Subjects aged 20-65 years old, 3.18 = BMI = 29.
Exclusion criteria
Exclusion criteria: 1.Patients who are allergic to experimental drugs or have other contraindications 2.With serious heart,lung, liver, kidney and brain diseases 3.Patients with history of mental disorders, chronic pain, or abnormal pain perception 4.Recent history of pain, including surgery and trauma 5.Alcoholics who have been taking sedatives or dependence on sedatives for a long time 6.Pregnant and lactating women 7.For other reasons, they were not considered suitable subjects for study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain threshold; | — |
Secondary
| Measure | Time frame |
|---|---|
| Degree of pain; | — |
Countries
China
Contacts
Public ContactLu Yao
The Second People's Hospital of Wuhu
Outcome results
None listed