colorectal cancer
Conditions
Interventions
Chemotherapy observation group:Nil
Non Chemotherapy observation group:Nil
Sponsors
Shenzhen Second People Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18-75 years; 2) Both male and female; 3) Colorectal cancer (CRC) was confirmed by pathology and clinical examination; 4) CRC at any T / N stage with M0 stage; 5) Those case with CRC will be treated by using chemotherapy regimen including fluorouracil, oxaliplatin and irinotecan; 6) KPS score >= 60; 7) The expected survival time was more than 6 months; 8) Sign informed consent.
Exclusion criteria
Exclusion criteria: 1) Colorectal cancer patients with distant metastasis; 2) Patients with CRC have chemotherapy history or undergoing chemotherapy; 3) Patients with multiple primary tumors; 4) The estimated survival time was less than 6 months; 5) Cachexia, malnutrition and failure of important organs; 6) Pregnant or lactating women; 7) Severe cardiopulmonary functional insufficiency; 8) Using other experimental drugs or participating in other clinical trials at the same time; 9) Any clinically relevant disease that may affect study participation and / or study results; 10) Drug allergy; 11) Patients with mental disorders and Alzheimer's disease; 12) Patients who the researchers believe are unwilling or unable to follow the study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Genetic testing;tumor burden;Immune evaluation;Survival time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Toxic reaction;KPS; | — |
Countries
China
Contacts
Public ContactZhang haitao
Shenzhen Second People Hospital
Outcome results
None listed