traumatic brain injury
Conditions
Interventions
1:phrenic nerve electrical stimulation combined with NAVA functional ventilator
Sponsors
Yijishan Hospital, Wannan Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with traumatic brain injury; 2. Aged >= 18 to 80 years; 3. NAVA ventilation time > 72 h; 4. Ventilator parameter setting: positive end expiratory pressure (PEEP) <= 8 cmH2O (1 cmH2O=0.098 kPa), inhaled oxygen Concentration (FiO2) <= 0.60; 5. The patient has a certain degree of spontaneous breathing ability and can trigger the ventilator to breathe; 6. The skin of the sternocleidomastoid area is completely exposed; 7. The patients family members sign an informed consent.
Exclusion criteria
Exclusion criteria: 1) Contraindications for phrenic nerve stimulation (severe lung infection, severe esophageal hemorrhage and obstruction perforation, diaphragmatic hernia, pneumothorax, active tuberculosis, pleural thickening adhesion, severe arrhythmia , Hemodynamic instability, metal implants in the body), etc.; 2) Severe central respiratory depression, high paraplegia, myasthenia gravis or known abnormal anatomy of the diaphragm; 3) Combined with sepsis, blood flow Dynamically unstable, ejection fraction less than 30%; 4) Mean arterial pressure (MAP) < 65 mmHg (1 mmHg = 0.133 kPa); 5) History of non-invasive/invasive mechanical ventilation and tracheotomy within 1 month before surgery Open history; 6) Acute myocardial infarction or cardiogenic shock occurred 72 hours before surgery; 7) Pregnant or lactating women; 8) Patients with unclear diagnosis; 9) Critically ill and unable to undergo surgery or other interventions; 10) Hospice patients; 11) Medically diagnosed as brain death.
Countries
China
Contacts
Public ContactTao Yu
Yijishan Hospital, Wannan Medical College
Outcome results
None listed