AIDS/COVID-19
Conditions
Interventions
non-exposed group 1: non-HIV patients vaccinated with SARS-CoV-2 vaccines:Nil
non-exposed group 2: HIV-patients without SARS-CoV-2 vaccines:Nil
exposure group: HIV-patients vaccinated with SARS-CoV-2 vaccines:Nil
Sponsors
The First Affiliated Hospital of China Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Exposure group (HIV infected persons vaccinated with new crown vaccine): (1) Those who were HIV positive by Western blotting and had a confirmed HIV report. (2) Subjects aged 18-65 years old. (3) The subjects who were recently vaccinated with new crown vaccine. (4) The subjects who signed the written informed consent for the investigation contents and laboratory testing items of the project. (5) Subjects willing to participate in the 9-month follow-up survey. 2. Non exposure group 1 (non HIV infected subjects vaccinated with the new crown vaccine) 1. Subjects with negative HIV antibody by rapid blood test. 2. Articles 2-5 are the same as those in the exposure group. 3. Subjects matched with the characteristics of HIV infected people who enrolled in the project. 3. Non exposure group 2 (HIV infected subjects who were not vaccinated with the new crown vaccine) (1) Western blot was used to detect HIV antibody positive subjects with confirmed HIV diagnosis report. (2) Subjects aged 18-65 years old. (3) Subjects who were not vaccinated with neocrown vaccine. (4) The subjects who signed the written informed consent for the investigation contents and laboratory testing items of the project. (5) Subjects willing to participate in the 9-month follow-up survey.
Exclusion criteria
Exclusion criteria: 1. Exposure group (HIV infected persons vaccinated with new crown vaccine): (1) Patients with severe mental and neurological disorders. (2) Patients with mental retardation or inability to communicate effectively with researchers. 2. Non exposure group 1 (non HIV infected subjects vaccinated with the new crown vaccine) (1) The above two exclusion criteria are the same as those for HIV infected people. (2) HIV fast test positive subjects. 3. Non exposure group 2 (HIV infected subjects who were not vaccinated with the new crown vaccine) (1) Patients with severe mental and neurological disorders. (2) Subjects with mental retardation or inability to communicate effectively with researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Side effects after SARS-CoV-2 vaccination;HIV viral load;SARS-CoV-2 neutralizing antibody;CD4+T cell count; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inhibitory /Cytotoxic T lymphocytes; | — |
Countries
China
Contacts
Public ContactJunjie Xu
The First Affiliated Hospital of China Medical University
Outcome results
None listed