Vocal cord paralysis related to Prolonged Mechanical Ventilation
Conditions
Interventions
vocal cord paralysis group vs. non vocal cord paralysis group:Nil
Sponsors
Zhongnan Hospital of Wuhan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: In the Department of critical care medicine, Central South Hospital of Wuhan University, adult patients (>= 18 years old) who underwent tracheal intubation and mechanical ventilation for more than 24 hours were screened continuously.
Exclusion criteria
Exclusion criteria: 1. Patients who had undergone tracheostomy before mechanical ventilation; 2. Patients with known laryngeal or tracheal diseases, such as bulbar palsy; 3. Patients with history of head and neck radiotherapy; 4. Those with coma (GCS < 9); 5. Those patients who were intubated during CPR; 6. Subjects with speech disorders; 7. Patients with contraindications to bronchoscopy; 8. Patients with chronic neuromuscular diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of vocal cord paralysis;Incidence and clinical manifestations of laryngeal discomfort after extubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence and clinical manifestations of throat discomfort 28 days after extubation;Incidence and clinical manifestations of throat discomfort 60 days after extubation;28 days mortality after extubation;Mechanical ventilation time;length of ICU stay;length of hospital stay;Pulmonary infection worsens after extubation or new infection appears;Tracheotomy rate;Re-intubation; | — |
Countries
??
Contacts
Public ContactBo Hu
Zhongnan Hospital of Wuhan University
Outcome results
None listed